International Journal of Science and Technology

International Journal of Science and Technology>> Volume 7, Number 7, July 2017

International Journal of Science and Technology


A Review of Artemisia annua L.: Its Genetics, Biochemical Characteristics, and Anti-Malarial Efficacy

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Author Lea C. Garcia
On Pages 37-45
Volume No. 5
Issue No. 2
Issue Date February 01, 2015
Publishing Date February 01, 2015
Keywords artemisinin, biochemical property, anti-malarial efficacy, mechanism of action, essential oil


Abstract

This paper presents a review on the genetics of A. annua as an important plant species for the treatment of malaria. A short history on the discovery of the plant is discussed. Furthermore, a clear description of the characteristics of A. annua is presented as the plantís chemistry, mechanism of action and efficacy are thoroughly discussed. Many cytogenetic studies on A. annua focusing on the production of the antimalarial drug, artemisinin are also presented. New technologies on artemisinin production are also discussed focusing on the use of microorganisms. The last part of the review discusses issues and future prospects of A. annua and artemisinin production for malaria therapy.

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