International Journal of Science and Technology

International Journal of Science and Technology>> Volume 7, Number 9, September 2017

International Journal of Science and Technology

Antihypertensive Properties of the Root and Stem Bark of Nauclea Latifoia Serum Electrolyte Profile

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Author Odey M. O., 2 Itam E. H., Ebong P. E., Atangwho I. J., Iwara I. A., Eyong U. E., Nnaligu I. J., Inekwe V. U., Johnson J. T., Ochigbo V., Udiba U. U., and Gauje B.
On Pages 382-385
Volume No. 2
Issue No. 6
Issue Date June, 2012
Publishing Date June, 2012
Keywords Nauclea latifolia, antihypertensive properties, serum electrolytes.


Hypertension is a relatively common disorder that is probably the most important public health problem in developed countries. It is common, asymptomatic, readily detectable, usually easily managed and usually leads to lethal complications if left unmanaged. This study evaluates the antihypertensive properties of the root and stem of Nauclea latifolia, by assessing the serum electrolytes levels in hypertensive animals treated with the extracts. The stem extract produced a significant decrease (p<0.05) of sodium in the treated animals compared to that of the hypertensive. The chloride levels in the treated and control groups were not significant (p>0.05), and the potassium levels were insignificant in the treated and control groups (p>0.05). Also, the potassium levels for the root extract treated animals were insignificantly lower (p>0.05) than the controls, while the sodium and chloride levels were significant (p<0.05). The reduced levels of these electrolytes, especially sodium showed that the N. latifolia extracts have antihypertensive properties.

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