International Journal of Science and Technology

International Journal of Science and Technology>> Volume 7, Number 9, September 2017

International Journal of Science and Technology


Isoniazid-Associated Uric Acid Retention in the Lizard, Uromastix HardwickII

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Author Ruqaiya Hasan, Soubia Malik, Ghazala Yasmeen, Mahmood Ahmad
On Pages 631-633
Volume No. 2
Issue No. 9
Issue Date September, 2012
Publishing Date September, 2012
Keywords Uric acid retention, Isoniazid, lizard.


Abstract

A study has been made on the reduction of uric acid excretion following oral administration of 0.06 mg Isoniazid (INH) per day for 5, 10 and 15 days to 3 batches of Uromastix hardwickii respectively. The rise of uric acid concentration in the blood was 60 per cent higher on day 5; and about 4 and 5 times greater than controls on day 10 and 15 respectively due to increased reabsorption or decreased excretion of uric acid from tubular fluid.

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